MSH2 Mouse Monoclonal Antibody [Kloon ID: UMLBI259]

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Carrier-free (BSA/glycerol-free) MSH2 mouse monoclonal antibody, clone UMLBI259

COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2

Homo sapiens mutS homolog 2 (MSH2), transcript variant 1, mRNA.

4436

P43246

Unconjugated

Colorectal cancer, Mismatch repair, Pathways in cancer

Colorectal cancer, Mismatch repair, Pathways in cancer

IHC 1:2400

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Stem cell - Pluripotency

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MSH2

https://www.ncbi.nlm.nih.gov/gene/?term=4436

https://www.uniprot.org/uniprot/P43246