
MSH3 Polyklonale Antilichaam, FITC Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Component of the post-replicative DNA mismatch repair system (MMR) . Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Divergent upstream protein; DNA mismatch repair protein; DNA mismatch repair protein Msh 3; DNA mismatch repair protein Msh3; DUC 1; DUC1; DUG; DUP; hMSH3; Mismatch repair protein 1; MRP 1; MRP1; MSH 3; MSH-3; MSH3_HUMAN; MutS homolog 3.
4437
Cytoplasm, Nucleus
• Rabbit
651-750/1137
MSH3
• Polyclonal
• IgG
FITC
KLH conjugated synthetic peptide derived from human MSH3
IF (IHC-P), IF (IHC-F), IF (ICC)
Purified by Protein A.
494nm/518nm
1µg/µl
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
4437
Human, Mouse, Rat, Dog, Cow, Rabbit
Beschrijving
MSH3 Polyklonale Antilichaam, FITC Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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