MTCH2 Antilichaam

This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.

23788

Q9Y6C9

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 30-175 of human MTCH2 (NP_055157.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Signal Transduction

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 33kDa

IgG

MTCH2

HeLa

293T

HT-29

Mouse small intestine

Mouse brain

Mitochondrial carrier homolog 2

Homo sapiens

Mitochondrial carrier homolog 2, Met-induced mitochondrial protein, MTCH2, MIMP

WB, IHC, IF

Liquid