MTERFD2 Antilichaam

MTERFD2 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung liver and kidney. MTERFD2 has been suggested to play a role in organ differentiation during embryogenesis. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.

130916

Q7Z6M4

NP_872307

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

MTERFD2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1308 - Human Small Intestine Tissue Lysate

1 mg/mL

MTERFD2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

MTERFD2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

At least three isoforms of MTERFD2 are known to exist. MTERFD2 antibody is predicted to not cross-react with other MTERFD protein family members.

MTERFD2

Cat. No. 11-801 - Human Small Intestine Tissue Slide

MTERF domain containing 2

Homo sapiens

Fernandez-Silva P, et al. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 1997; 16:1066-79.

Xu Q, Zhang F, He H, et al. Expression profile of mouse Mterfd2, a novel component of the mitochondrial transcription termination (MTERF) family. Genes Genet. Syst. 2011; 86:269-75.

Park CB, Asin-Cayuela J, Camara Y, et al. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell 2007; 130:273-85.

MTERFD2 Antibody: MTERF4, mTERF domain-containing protein 2, Mitochondrial transcription termination factor 4, MTERF4

ELISA, WB, IHC-P, IF

42740903

Liquid