MTERFD3 Antilichaam

MTERFD3 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD3 was initially identified through differential display analysis and is expressed primarily in heart, liver, pancreas and skeletal muscle. MTERFD3 is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription, and may be a serum-inhibitory factor.

80298

Q49AM1

NP_079474

Human, Mouse

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

MTERFD3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1313 - Human Testis Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Rat: (76%)

MTERFD3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

MTERFD3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

MTERFD3 antibody is predicted to not cross-react with other MTERFD protein family members.

MTERFD3

MTERF domain containing 3

Homo sapiens

Fernandez-Silva P, et al. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 1997; 16:1066-79.

Chen Y, Zhou G, Yu M, et al. Cloning and functional analysis of human mTERFL encoding a novel mitochondrial transcription termination factor-like protein. Biochem. Biophys. Res. Commun. 2005; 337:1112-8.

Park CB, Asin-Cayuela J, Camara Y, et al. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell 2007; 130:273-85.

MTERFD3 Antibody: mTERF2, mTERFL, mTERF domain-containing protein 3, mitochondrial, Mitochondrial transcription termination factor 2, mTERF2

ELISA, WB, IHC-P

21314736

Liquid