MTMR3 Antilichaam

This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol (3) -phosphate and phosphatidylinositol (3,5) -biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.

8897

Q13615

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 640-810 of human MTMR3 (NP_066576.1) .

Unconjugated

Primary Antibodies

Autophagy, Cell Cycle, Signal Transduction

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 134kDa

IgG

MTMR3

HeLa

Jurkat

LO2

Myotubularin related protein 3

Homo sapiens

FYVE-DSP1, ZFYVE1myotubularin-related protein 3, FYVE (Fab1 YGLO23 Vsp27 EEA1 domain) dual-specificity protein phosphatase, FYVE domain-containing dual specificity protein phosphatase 1, phosphatidylinositol-3,5-bisphosphate 3-phosphatase, phosphatidylinositol-3-phosphate phosphatase, zinc finger FYVE domain-containing protein 1zinc finger, FYVE domain containing 10

WB, IF

Liquid