MTNR1A Antilichaam

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

4543

P48039

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 281-350 of human MTNR1A (NP_005949.1) .

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 39kDa

IgG

MTNR1A

Mouse small intestine

Rat small intestine

Rat kidney

Melatonin receptor 1A

Homo sapiens

MTNR1A, melatonin receptor 1A, MEL-1A-R, MT1, melatonin receptor type 1A

WB, IHC

Liquid