MTOR antilichaam

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Serine/threonine-protein kinase mTOR|FK506-binding protein 12-rapamycin complex-associated protein 1|FKBP12-rapamycin complex-associated protein|Mammalian target of rapamycin (mTOR) |Mechanistic target of rapamycin|Rapamycin and FKBP12 target 1|Rapamycin target protein 1|MTOR|FRAP|FRAP1|FRAP2|RAFT1|RAPT1

2475

P42345

Human, Mouse, Rat

FK506 binding protein 12-rapamycin associated protein 1

MTOR

Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Cell Division and Proliferation

Protein A affinity purified

WB: 1:1000 - 1:10000; IHC: 1:500 - 1:2000; IF:1:200-1:800

≥95% as determined by SDS-PAGE

Liquid

290 kDa

4°C with ice bag

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

5G5

ELISA, WB, IHC, IF

27-291aa