MUT Antilichaam / Methylmalonyl-CoA mutase

Methylmalonyl-CoA mutase (MUT) is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. This gene is mapped to 6p12.3. MUT requires a vitamin B12-derived prosthetic group, adenosylcobalamin (commonly referred to as AdoCbl), to function. And the product of this enzyme, succinyl-CoA, is a key molecule of the TCA cycle.

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells

P22033

Human, Mouse, Rat

Amino acids 33-65 (LHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPE-human) were used as the immunogen for the MUT antibody.

WB, IHC-P, FACS

Antigen affinity

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

This MUT antibody is available for research use only.

After reconstitution, the MUT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the MUT antibody should be determined by the researcher.

Immunohistochemical staining of FFPE human bladder urothelial carcinoma tissue with MUT antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.