Muurol-4-een-3,8-dion

Muurol-4-ene-3,8-dione (Compound 2), a sesquiterpene, is one of the main hepatotoxic components in Eupatorium adenophorum. Muurol-4-ene-3,8-dione has an inhibitory effect on the growth of both the normal human hepatocyte cell L02 and the human hepatocellular carcinoma cell HepG2 with IC50 values of 87.52 and 104.48 μM[1].

105181-07-5

12352211

Others

Others

Metabolic Disease

[H][C@]12C=C(C(C[C@@]([C@H](C)CC([C@@H]2C(C)C)=O)1[H])=O)C

C15H22O2

234.33

[1]Liu B, Cao L, Zhang L, Yuan X, Zhao B. Hepatotoxicity of Eupatorium adenophorum extracts and the identification of major hepatotoxic components. Nat Prod Res. 2017 Dec;31 (23) :2788-2792.|[2]Liu B, Cao L, Zhang L, Yuan X, Zhao B. Hepatotoxicity of Eupatorium adenophorum extracts and the identification of major hepatotoxic components. Nat Prod Res. 2017 Dec;31 (23) :2788-2792.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N16513/

Natural Products

No Development Reported