MXD4 Antilichaam - N-terminaal gebied: Biotine (ARP32777 T100-Biotine)

MAX dimerization protein 4

MAD4, MST149, MSTP149, bHLHc12

10608

Q14582

NP_006445

Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the N terminal region of human MXD4

MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.

TCP10L; UBC; SHBG; SIN3A; MLX; MAX; SMC3

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Sheep: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

24kDa

Marcotte, R., et al., (2005) J. Cell. Biochem. 96 (5), 1071-1085

Wet Ice

209

MXD4

MXD4

Rabbit

Max dimerization protein 4

NM_006454

SLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNN