MYBPC3 Mouse Monoclonal Antibody [Kloon ID: LBI2F1]

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) MYBPC3 mouse monoclonal antibody, clone LBI2F1

CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C

Homo sapiens myosin binding protein C3 (MYBPC3), mRNA.

4607

Q14896

Unconjugated

Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

ELISA 1:5000-10000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MYBPC3

https://www.ncbi.nlm.nih.gov/gene/?term=4607

https://www.uniprot.org/uniprot/Q14896