Myc (fosfo Thr58) Antilichaam

Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

4609

P01106

NP_002458.2

Human, Mouse, Rat

Myc (Phospho-Thr58) antibody was raised against a peptide sequence around phosphorylation site of threonine 58 (L-P-T (p) -P-P) derived from Human Myc.

Unconjugated

Primary Antibodies

Phospho-Specific, Apoptosis, Cancer, Cell Cycle

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

60 kDa

This antibody detects endogenous level of Myc only when phosphorylated at threonine 58.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

MYC

V-myc avian myelocytomatosis viral oncogene homolog

Homo sapiens

Jin Z, et al. (2004) J Biol Chem. 279 (38) : 40209-40219. Welcker M, et al. (2004) Proc Natl Acad Sci U S A. 101 (24) : 9085-9090. Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182.

MRTL, MYCC, c-Myc, bHLHe39, BBC6, BCL2L8, c-myc

WB, IHC

71774083

Liquid