MYCN Antibody - C-terminal regio : HRP (ARP32030 T100-HRP)

V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

NMYC, ODED, MODED, N-myc, bHLHe37

4613

P04198

NP_005369

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN

MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas

TRIM32; UBC; HDAC5; NMI; MAX; CDKN2A; GRK5; ZBTB17; SIRT1; YEATS4; CSNK1E; FBXW7; PIAS2; AURKA; SP1; NTRK1; NGFR; HDAC2; CSNK2A1; YAF2; MXD1; CSNK2A2; SLC1A2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 77%; Rat: 92%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Hansford, L.M., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (34), 12664-12669

Wet Ice

464

MYCN

MYCN

Rabbit

N-myc proto-oncogene protein

NM_005378

EDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILER