MYD88 Mouse Monoklonale Antilichaam [Kloon ID: LBI1B4]

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) MYD88 mouse monoclonal antibody, clone LBI1B4

MYD88D

Homo sapiens MYD88 innate immune signal transduction adaptor (MYD88), transcript variant 2, mRNA.

4615

Q99836

Unconjugated

Apoptosis, Toll-like receptor signaling pathway

Apoptosis, Toll-like receptor signaling pathway

WB 1:2000, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MYD88

https://www.ncbi.nlm.nih.gov/gene/?term=4615

https://www.uniprot.org/uniprot/Q99836