MYLIP Polyklonale Antilichaam, Biotinevervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
MIR; IDOL; E3 ubiquitin-protein ligase MYLIP; Inducible degrader of the LDL-receptor; Myosin regulatory light chain interacting protein; MYLIP; BZF1; BM-023; PP5242
29116
Q8WY64
Cell membrane
• Rabbit
Human
51-150/445
MYLIP
• Polyclonal
• IgG
Biotin
KLH conjugated synthetic peptide derived from human MYLIP
WB, IHC-P
Purified by Protein A.
1µg/µl
WB (1:300-5000), IHC-P (1:200-400)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C for 12 months.
29116
Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit
Beschrijving
MYLIP Polyklonale Antilichaam, Biotinevervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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