MYO6 Antilichaam

This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

4646

Q9UM54

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 150kDa

IgG

MYO6

Mouse brain

Mouse kidney

Myosin VI

Homo sapiens

DFNA22, DFNB37, unconventional myosin-VI, unconventional myosin-6

WB, IF

Liquid