MYOC Antibody - N-terminal regio : FITC (ARP59771 P050-FITC)

Myocilin, trabecular meshwork inducible glucocorticoid response

GPOA, JOAG, TIGR, GLC1A, JOAG1

4653

Q99972

NP_000252.1

Human, Rat, Guinea Pig

The immunogen is a synthetic peptide directed towards the N-terminal region of human MYOC

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR) . The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Guinea Pig: 86%; Human: 100%; Rat: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

37kDa

Wet Ice

344

MYOC

MYOC

Rabbit

Myocilin

NM_000261.1

QLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKS