Myocytversterkerfactor 2B Adenovirus (Ad-MEF2B)

Differentiation of myogenic cells is regulated by multiple positive and negative regulators. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes MyoD, myogenin, Myf-5, Myf-6 (also designated MRF-4 or herculin) and musculin (also designated MyoR) . Members of this group of transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, ITF2 and HEB. The E2A gene encodes at lest two different proteins, E12 and E47, as a result of alternative splicing. The myocyte enhancing factor-2 (MEF-2) family of transcription factors includes four splice variants A, B, C and D which encode muscle-specific DNA binding proteins that recognize an A/T rich sequence [CTA (A/T) 4 TAG] localized in the control regions of numerous muscle-specific genes.

Myocyte enhancer factor 2B Adenovirus

41106621

3822190000

Pre-Made

Dry Ice

-80C

12 Months

Ad-MEF2B

Human Adenovirus Type5 (dE1/E3)

CMV (ubiquitous)

DMEM, 2% BSA, 2.5% Glycerol

1x10^10 PFU/ml