MYOF Antilichaam

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

26509

Q9NZM1

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MYOF (NP_038479.1) .

Unconjugated

Primary Antibodies

Cell Cycle

Affinity purification

U-251MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 250kDa

IgG

WB: 1:200 - 1:2000

MYOF

A-549

HeLa

NIH/3T3

Myoferlin

Homo sapiens

FER1L3, myoferlin, fer-1-like 3, myoferlin, fer-1-like family member 3, fer-1-like protein 3

WB

Liquid