Myristoyltetrapeptide-12

Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA. Myristoyl tetrapeptide-12 is capable of stimulating hair growth, especially at the level of eyelashes[1][2].

959610-24-3

12352209

H302-H315-H319-H335

TGF-beta/Smad

Stem Cell/Wnt; TGF-beta/Smad

Metabolism-protein/nucleotide metabolism

Metabolic Disease

10 mM in DMSO

C[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC(CCCCCCCCCCCCC)=O)=O)=O)=O

C32H63N7O5

625.89

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

[1]Haeyoung Kwon, et al. Smad-induced alterations of matrix metabolism by a myristoyl tetra peptide. Cell Biochem Funct. 2014 Dec;32 (8) :665-74.|[2]C. Diehl. Peptides in cosmeceuticals. ISSN 1727-5741 (Print), ISSN 2522-1035 (Online) .

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W108953/

Peptides

No Development Reported