MYT1 (fosfo Ser83) Antilichaam

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

9088

Q99640

XP_006721039.1

Human

MYT1 (phospho Ser83) antibody was raised against a peptide sequence around phosphorylation site of Serine 83 (R-V-S (p) -F-R) derived from Human MYT1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

54 kDa

IgG

The antibody detects endogenous levels of MYT1 only when phosphorylated at serine 83.

PKMYT1

Protein kinase, membrane associated tyrosine/threonine 1

Homo sapiens

Booher R.N., J. Biol. Chem. 272:22300-22306 (1997) .

Liu F., Mol. Cell. Biol. 17:571-583 (1997) .

Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396 (2006) .

PMYT1, PKMYT1, MYT1 kinase

IHC

33383241

Liquid