MYT1L Antilichaam

MYT1L Antibody: The myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.

23040

Q9UL68

NP_055840

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Neuroscience

MYT1L Antibody is affinity chromatography purified via peptide column.

Cat. No. 1403 - Mouse Brain Tissue Lysate

1 mg/mL

MYT1L Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

MYT1L antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

130 kDa

IgG

At least three isoforms are known to exist. This antibody will only recognize the two longest isoforms.

MYT1L

Myelin transcription factor 1-like

Homo sapiens

Romm E, Nielsen JA, Kim JG, et al. Myt1 family recruits histone deacetylase to regulate neural transcription. J. Neurochem. 2005; 93:1444-53

Li W, Wang X, Zhao J, et al. Association study of myelin transcription factor 1-like polymorphisms with schizophrenia in Han Chinese population. Genes Brain Behav. 2012; 11:87-93.

MYT1L Antibody: NZF1, ZC2HC4B, KIAA1106, Myelin transcription factor 1-like protein, MyT1-L

ELISA, WB, IF

60498973

Liquid