MZ1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MZ1 consists of JQ1 tethered to a ligand for the E3 ubiquitin ligase VHL and is a selective degrader of the BET bromodomain protein BRD4. It rapidly and potently induces reversible, long-lasting and unexpectedly selective degradation of BRD4 over BRD2 and BRD3.1 It exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B.2 An important tool for studying the effects of BRD4 degradation in cancer therapy.3
Unconjugated
Pale-yellow solid
-20°C
Beschrijving
MZ1 Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
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