N-Acetyl-S- (3,4-dihydroxybutyl) -L-cysteïne

N-Acetyl-S- (3,4-dihydroxybutyl) -L-cysteine (Dihydroxybutyl mercapturic acid) is a biomarkersof 1,3-butadiene exposure. 1,3-Butadiene is a known human carcinogen present in cigarette smoke and in automobile exhaust.

144889-50-9

Dihydroxybutyl mercapturic acid; DHBMA

12352211

H302-H315-H319-H335

Others

Others

Others

O=C(O)[C@H](CSCCC(O)CO)NC(C)=O

C9H17NO5S

251.30

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

[1]Park SL, Kotapati S, Wilkens LR, et al. 1,3-Butadiene exposure and metabolism among Japanese American, Native Hawaiian, and White smokers. Cancer Epidemiol Biomarkers Prev. 2014;23 (11) :2240-2249.|[2]Kotapati S, Matter BA, Grant AL, Tretyakova NY. Quantitative analysis of trihydroxybutyl mercapturic acid, a urinary metabolite of 1,3-butadiene, in humans. Chem Res Toxicol. 2011;24 (9) :1516-1526.|[3]Lin CY, Lee HL, Jung WT, Sung FC, Su TC. The association between urinary levels of 1,3-butadiene metabolites, cardiovascular risk factors, microparticles, and oxidative stress products in adolescents and young adults. J Hazard Mater. 2020;396:122745.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W587741/

Reference compound2

No Development Reported