N-acetyldopamine (standaard)

N-acetyldopamine is a sepiapterin reductase inhibitor. N-acetyldopamine is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle. N-acetyldopamine can attenuate LPS-stimulated TNF-α production and superoxide production in THP-1 cells[1][2].

2494-12-4

12352005

Endogenous Metabolite; Reactive Oxygen Species (ROS) ; TNF Receptor

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Others

CC(NCCC1=CC=C(O)C(O)=C1)=O

C10H13NO3

195.22

[1]Hanine Barek, et al. Unraveling Complex Molecular Transformations of N-β-alanyldopamine That Account for Brown Coloration of Insect Cuticle. Rapid Commun Mass Spectrom. 2017 Aug 30;31 (16) :1363-1373.|[2]Perianayagam, M. C., et al., (2005) . Immune-modulating effects of melatonin, N-acetylserotonin, and N-acetyldopamine. Annals of the New York Academy of Sciences, 1053, 386–393.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N7493R/

Reference Standards