N-Desbutylbupivacaine

N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine , an NMDA receptor inhibitor and SCN5A antagonist[1][2].

15883-20-2

Desbutylbupivacaine

12352005

H301

Drug Metabolite

Metabolic Enzyme/Protease

Neurological Disease

99.92

CC1=CC=CC(C)=C1NC(C2CCCCN2)=O

C14H20N2O

232.32

H301

[1]Meaghan A Paganelli, et al. Actions of Bupivacaine, a widely used local anesthetic, on NMDA receptor responses. J Neurosci. 2015 Jan 14;35 (2) :831-42.|[2]Alexander P Schwoerer, et al. A Comparative Analysis of Bupivacaine and Ropivacaine Effects on Human Cardiac SCN5A Channels. Anesth Analg. 2015 Jun;120 (6) :1226-34.

Room Temperature

4°C (Powder, protect from light)

http://file.medchemexpress.com/batch_PDF/HY-W045132/

Reference compound1

No Development Reported