N-Desbutylbupivacaine-d6
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
N-Desbutyl bupivacaine-d6 (Desbutylbupivacaine-d6) is the deuterium labeled N-Desbutyl Bupivacaine. N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist[1][2].
Desbutylbupivacaine-d6
12352005
Drug Metabolite; Isotope-Labeled Compounds
Metabolic Enzyme/Protease; Others
Neurological Disease
O=C(C1CCCCN1)NC2=C(C([2H])([2H])[2H])C=CC=C2C([2H])([2H])[2H]
C14H14D6N2O
238.36
[1]Meaghan A Paganelli, et al. Actions of Bupivacaine, a widely used local anesthetic, on NMDA receptor responses. J Neurosci. 2015 Jan 14;35 (2) :831-42.|[2]Alexander P Schwoerer, et al. A Comparative Analysis of Bupivacaine and Ropivacaine Effects on Human Cardiac SCN5A Channels. Anesth Analg. 2015 Jun;120 (6) :1226-34.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W045132S/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
N-Desbutyl bupivacaine-d6 (Desbutylbupivacaine-d6) is the deuterium labeled N-Desbutyl Bupivacaine. N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bup
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