N-gemethyleerd pomalidomide
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
N-methylated pomalidomide (Pomalidomide-methyl), a derivative of Pomalidomide , is a cereblon (CRBN) ligand. N-methylated pomalidomide is unable to recruit CRBN that can be used as a negative control for Pomalidomide. N-methylated pomalidomide can be used to synthesize PROTAC[1].
1352827-50-9
Pomalidomide-methyl
12352005
H302, H312, H332, H361
Ligands for E3 Ligase
PROTAC
Cancer-programmed cell death
Cancer
97.86
O=C1C2=C(C(N1C3C(N(C)C(CC3)=O)=O)=O)C(N)=CC=C2
C14H13N3O4
287.27
H302, H312, H332, H361
[1]Yokoo H, et al. Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer. ACS Med Chem Lett. 2021 Jan 14;12 (2) :236-241.
Room Temperature
4°C (Powder, protect from light)
http://file.medchemexpress.com/batch_PDF/HY-W586822/N-Methylated-pomalidomide-SDS-MedChemExpress.pdf
Reference compound1
No Development Reported
Cereblon
Beschrijving
N-methylated pomalidomide (Pomalidomide-methyl), a derivative of Pomalidomide , is a cereblon (CRBN) ligand. N-methylated pomalidomide is unable to recruit CRBN
Specificaties
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