N1-Fenylsuberamide

N1-Phenylsuberamide is an organic amide compound, and its structure can be regarded as a simplified analogue of Vorinostat. N1-Phenylsuberamide exhibits moderate anti-proliferative activity against MDA-MB-231 and MCF-7 cells. N1-Phenylsuberamide does not show significant HDAC inhibitory activity and can only weakly induce the expression of the p21 gene. N1-Phenylsuberamide has extremely low relative binding affinity of estrogen receptor. N1-Phenylsuberamide can be used as a control compound[1].

1305124-48-4

12352005

H302-H315-H319-H335

Drug Derivative

Others

Cancer

O=C(CCCCCCC(NC1=CC=CC=C1)=O)N

C14H20N2O2

248.32

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

[1]Cázares Marinero Jde J, et al. Efficient new constructs against triple negative breast cancer cells: synthesis and preliminary biological study of ferrocifen-SAHA hybrids and related species. Dalton Trans. 2013 Nov 21;42 (43) :15489-501.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-Z12208/

Reference compound1

No Development Reported