Na+-Ca2+ Wisselaar

Na+-Ca2+ Exchanger inhibitory peptide (XIP) is a Na+-Ca2+ exchanger inhibitor with a Ki of 200 nM. Na+-Ca2+ Exchanger inhibitory peptide inhibits the Na+-dependent Ca2+ uptake and the Na+-dependent Ca2+ efflux of sarcolemmal vesicles in a noncompetitive manner[1].

XIP

12352209

Na+/Ca2+ Exchanger

Membrane Transporter/Ion Channel

Neurological Disease

O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](C(C)C)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

C112H161N27O33

2413.64

[1]Z Li, et al. Identification of a peptide inhibitor of the cardiac sarcolemmal Na (+) -Ca2+ exchanger. J Biol Chem. 1991 Jan 15;266 (2) :1014-20.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10811/

Peptides

No Development Reported