NAB815
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1969250-99-4
TLR, Antibacterial
Immunology/Inflammation, Microbiology/Virology
NAB815 is a specific inhibitor of Stx2a (Kd= 0.01 μM) /TLR4 interactions. It inhibits the interaction between neutrophils and Stx2a with an IC50 of 0.057 μg/mL. NAB815 also prevents the formation of extracellular vesicles (EV) containing Stx2 from leukocytes and platelets, reducing its toxicity in cells (Vero cells) and in animal models (CD-1 mice) . Additionally, NAB815 decreases the bacterial load in the kidneys, urine, and bladder of mice infected with Escherichia coli. It is applicable for research in hemolytic uremic syndrome (HUS) .
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C55H94N14O14
1175.42
Ice Packs
-20°C
Beschrijving
NAB815 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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