Naloxegol-13C, d3
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Naloxegol-13C, d3 (NKTR-118-13C, d3) is 13C labeled Naloxegol. Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation[1][2].
NKTR-118-13C, d3; AZ-13337019-13C, d3
12352211
Isotope-Labeled Compounds
Others
Cancer-programmed cell death
Neurological Disease; Cancer
O[C@]12[C@@]34C5=C(C[C@@]2([H])N(CC4)CC=C)C=CC(O)=C5O[C@@]3([H])[C@H](CC1)OCCOCCOCCOCCOCCOCCOCCO[13C]([2H])([2H])[2H]
C33 13CH50D3NO11
655.80
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-A0118S/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Naloxegol-13C, d3 (NKTR-118-13C, d3) is 13C labeled Naloxegol. Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid bi
Specificaties
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