NAP3 Antilichaam [Nalpy3-b]

114548

Q96P20

Human

NALP3 (monoclonal Nalpy3-b) antibody was raised against recombinant human NALP3.

Nalpy3-b

Unconjugated

Primary Antibodies

Apoptosis

NALP3 (monoclonal Nalpy3-b) antibody was purified from concentrated hybridoma tissue culture supernatant. NALP3 (monoclonal Nalpy3-b) antibody was purified to ≥95% in SDS-PAGE.

Batch dependent

PBS containing 0.02% sodium azide

None

Blue Ice

NALP3 antibody can be stored at 4˚ C, stable for one year.

IgG1

NALP3 antibody can be used to recognize human NALP3. It detects endogenous protein by Immunoprecipitation (1:50) and Western Blot (1:1,000) . This product is for research use only.

NLR family, pyrin domain containing 3

Homo sapiens

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder: L. Agostini, et al.; Immunity 20, 319 (2004) .

Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation: M. Chamaillard, et al.; Cell. Microbiol. 5, 581 (2003) .

Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties: W. O'Connor, Jr., et al.; J. Immunol. 171, 6329 (2003) .

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases: F. Martinon and J. Tschopp; Cell 117, 561 (2004) .

WB, IP

Liquid