Naperiglipron
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2572566-11-9
LY3549492
C18330-5mg
FC (C=C (C=C1) C#N) =C1COC2=NC (C (C (C) =C3) =CC (F) =C3CC4=NC5=CC=C (C (O) =O) C=C5N4C[C@H]6OCC6) =CC=C2
C33H26F2N4O4
Naperiglipron (LY3549492) (Example 2) acts as a glucagon-like peptide 1 receptor (GLP-1R) agonist, exhibiting an EC50 of 1.14 nM at hGLP-1R. In GLP-1R knock-in mouse models, it reduces blood glucose levels. The compound shows PDE10A1 enzyme inhibitory activity (IC50: 7.43 μM) and displays weak hERG inhibition. Naperiglipron has potential applications in type II diabetes mellitus (T2DM) and obesity studies.
Beschrijving
Naperiglipron Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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