Narciclasine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
29477-83-6
Lycoricidinol
STAT
Apoptosis
C14H13NO7
Narciclasine (Lycoricidinol), an isocarbostyril alkaloid narciclasine, targets STAT3 via distinct mechanisms in tamoxifen-resistant breast cancer cells. Narciclasine suppresses phosphorylation, activation, dimerization, and nuclear translocation of STAT3 by directly binding with the STAT3 SH2 domain and leads STAT3 degradation. Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.
3 years -20°C powder
Beschrijving
Narciclasine Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
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