NAT11 Antilichaam

NAT11 Antibody: N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring on approximately 57% and 84% on yeast and human proteins respectively. There are several N-terminal acetylating enzyme complexes (NatA - NatE) . Unlike the other complexes, NatD is composed of a single protein, NAT11, and has recently been described to acetylate the Serine N-termini of histones H2A and H4 in yeast. The role these modifications play is unknown; yeast that do not express NAT11 grow at normal rates and have no observable phenotypes. The role of the human homolog is likewise unknown.

79829

Q86UY6

NP_079047

Human, Mouse

Unconjugated

Primary Antibodies

Homeostasis

NAT11 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1314 - Human Thymus Tissue Lysate

1 mg/mL

NAT11 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

NAT11 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

NAA40

N (alpha) -acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)

Homo sapiens

Arnesen T, Van Damme P, Polevoda B, et al. Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans. Proc. Natl. Acad. Sci. USA2009; 106:8157-62.

OK Song, Wang X, Waterborg JH, et al. An Nalpha-acetyl-transferase responsible for acetylation of the N-terminal residues of histones H4 and H2A. J. Biol. Chem.2003; 278:38109-1

NAT11 Antibody: NAT11, PATT1, NAT11, N-alpha-acetyltransferase 40, N-acetyltransferase 11

ELISA, WB, IHC-P, IF

189571650

Liquid