NAT2 Antilichaam

This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2) .

10

P11245

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 171-290 of human NAT2 (NP_000006.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 36kDa

IgG

NAT2

Mouse heart

Mouse liver

Mouse kidney

N-acetyltransferase 2 (arylamine N-acetyltransferase)

Homo sapiens

NAT2, AAC2, PNAT, NAT-2

WB, IHC, IF

Liquid