NAT2 Antilichaam - middelste regio : HRP (ARP44195_T100-HRP)

N-acetyltransferase 2 (arylamine N-acetyltransferase)

AAC2, PNAT, NAT-2

10

P11245

NP_000006

Human

The immunogen is a synthetic peptide directed towards the middle region of human NAT2

NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2) . This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2) . This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.

APP; NAA10

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32kDa

Tamer, L., (2006) Cell Biochem. Funct. 24 (2), 131-135

Wet Ice

Antibody reacts with both NAT1 and NAT2

290

NAT2

NAT2

Rabbit

Arylamine N-acetyltransferase 2

NM_000015

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