NAT6-297775
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
NAT6-297775 (Compound 29) is a protein tyrosine phosphatase (PTP) inhibitor targeting non-receptor PTP SHP-2 with an IC50 of 2.5 μM. NAT6-297775 can inhibit the RAS/MAP kinase signaling pathway. NAT6-297775 can be used for the research of cancer, such as leukemia[1].
1348433-02-2
12352005
Phosphatase; SHP2
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Cancer
N(CC1CCCCC1)[C@H]2O[C@@]3([C@H](CO[C@@]3(C2)[H])N4C(=NN=N4)C5=CC(CN6CCCC6)=CC=C5)[H]
C25H36N6O2
452.60
[1]Vintonyak VV, et al. Using small molecules to target protein phosphatases. Bioorg Med Chem. 2011 Apr 1;19 (7) :2145-55.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-180326/
Reference compound1
No Development Reported
Beschrijving
NAT6-297775 (Compound 29) is a protein tyrosine phosphatase (PTP) inhibitor targeting non-receptor PTP SHP-2 with an IC50 of 2.5 μM. NAT6-297775 can inhibit the
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