NBD-peptide

NBD peptide inhibits NF-κB signaling pathway through inhibition of the NEMO-IKK complex combination. NBD peptide exhibits anti-inflammatory efficacy through block of pro-inflammatory cytokines production. NBD peptide exhibits immunosuppressive activity through regulation of immune cells. NBD peptide enhances its transmembrane ability by combining with cell-penetrating peptide HIV-TAT[1].

371915-62-7

12352209

NF-κB

NF-κB

Inflammation/Immunology

O=C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CO)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N

C62H88N14O20

1349.44

[1]Zhou CL, et al., The latest developments in synthetic peptides with immunoregulatory activities. Peptides. 2011 Feb;32 (2) :408-14.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10839/

Peptides

No Development Reported