NBN Antilichaam, MY gevalideerd

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

4683

O60934

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 435-754 of human NBN (NP_002476.2) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cancer, Cell Cycle

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 110kDa

IgG

WB: 1:500 - 1:1000

NBN

HeLa

HepG2

Mouse liver

Nibrin

Homo sapiens

NIBRIN Antibody: ATV, NBS, P95, NBS1, AT-V1, AT-V2, Nibrin, Cell cycle regulatory protein p95

WB

Liquid