NCBP1 Antibody - N-terminal regio: FITC (ARP40396 P050-FITC)

Nuclear cap binding protein subunit 1, 80kDa

NCBP, Sto1, CBP80

4686

Q09161

NP_002477

Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human NCBP1

NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

POLDIP3; HUWE1; EIF4G1; UPF3B; EIF3B; MTOR; RPS6KB1; ALYREF; DDX39B; THOC3; THOC2; IVNS1ABP; UBC; LIN28B; LIN28A; ZNF346; SUMO1; SUZ12; EED; RNF2; BMI1; VAT1; MVP; TTC1; PPM1G; SERPINE2; NCL; NAP1L4; GFPT1; GARS; PUS1; TARDBP; YWHAE; RUVBL1; MPG; FN1; C17

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 88%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

92kDa

Narita, T., (2007) Mol. Cell 26 (3), 349-365

Wet Ice

790

NCBP1

NCBP1

Rabbit

Nuclear cap-binding protein subunit 1

NM_002486

SRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLE

1