NCOA1 Antilichaam - middengebied: Biotine (ARP3991 P050-Biotine)

Nuclear receptor coactivator 1

SRC1, KAT13A, RIP160, F-SRC-1, bHLHe42, bHLHe74

8648

Q15788-2

NP_671756

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human NCOA1

NCOA1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. NCOA1 binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

ASCC1; NR1I2; PPARG; AR; VDR; THRB; RXRA; RORB; RORA; RARA; HNF4G; NR6A1; NR5A2; ESRRA; ESR1; PAGR1; Esr2; NR3C1; CXADR; PPARA; AHR; KANK2; NCOA2; TRIM24; NCOA1; ANIB1; PGR; COPS5; UBE2L3; TP53; NCOA6; EP300; UBC; RARB; PPARD; RARG; RBBP6; CREBBP; STAT3

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

152kDa

Lavery, D.N. (2008) Biochemistry 47 (11), 3352-3359

Wet Ice

1399

NCOA1

NCOA1

Rabbit

Nuclear receptor coactivator 1

NM_147223

GLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSC