NCPD2 Antibody - C-terminal regio : HRP (ARP46210_P050-HRP)

Non-SMC condensin I complex, subunit D2

CNAP1, CAP-D2, MCPH21, hCAP-D2

9918

Q15021

NP_055680

Human, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human NCAPD2

NCAPD2 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. NCAPD2 may target the condensin complex to DNA via its C-terminal domain.

UBC; NCAPG; CCAR2; NCAPH; SMC2; SMC4; TXNL1; RABEP1; PABPC4; RPS5; FLNC; SOX2; CSNK2A1; PAXIP1; PNPT1; NUP153; MEA1; HSPD1; C1QBP; SIRT7; CDK1; RAD21; SIRT3; tat; PARP1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

NCAPD2 is supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Dog: 79%; Horse: 93%; Human: 100%; Pig: 92%; Rabbit: 92%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

157kDa

Lee, J.H., (er) Neurogenetics (2008) In press

Wet Ice

1401

NCAPD2

NCAPD2

Rabbit

Condensin complex subunit 1

NM_014865

KAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPSTGSRYQPL

1