NDE1 Antilichaam - middengebied: FITC (ARP47932 P050-FITC)

NudE nuclear distribution E homolog 1 (A. nidulans)

NDE, LIS4, MHAC, NUDE, NUDE1, HOM-TES-87

54820

Q9NXR1-2

NP_060138

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human NDE1

NDE1 is required for centrosome duplication and formation and function of the mitotic spindle. It is essential for the development of the cerebral cortex. NDE1 may regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex

FAM9B; LZTS2; USHBP1; NDEL1; ZNF398; NDE1; WAC; UBQLN1; MED4; DISC1; TFIP11; CEP250; NDC80; ARNT2; BZRAP1; MKRN3; TTC1; TRIM27; REL; HOXA2; GOLGA2; AR; YWHAQ; PAFAH1B1; ZNF365; YWHAG; TUBG1; MAPK1; CDK1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

NDE1 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

38kDa

Burdick, K.E., (er) Hum. Mol. Genet. (2008) In press

Wet Ice

335

NDE1

NDE1

Rabbit

Nuclear distribution protein nudE homolog 1

NM_017668

AHRGPSSSLNTPGSFRRGLDDSTGGTPLTPAARISALNIVGDLLRKVGAL