NDUFS2 Antilichaam

NDUFS2 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) . Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria.

4720

O75306

O75306

Human, Mouse

This NDUFS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human NDUFS2.

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Obesity, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

53 kDa

Rabbit Ig

NDUFS2

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

Homo sapiens

Saada, A., et al. Am. J. Hum. Genet. 84 (6) :718-727 (2009) Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17 (12) :3558-3566 (2008) Starr, J.M., et al. Mech. Ageing Dev. 129 (12) :745-751 (2008) Ban, M., et al. PLoS ONE (8), E2891 (2008) Triepels, R.H., et al. J. Biol. Chem. 276 (12) :8892-8897 (2001)

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial, Complex I-49kD, CI-49kD, NADH-ubiquinone oxidoreductase 49 kDa subunit, NDUFS2

WB, IHC-P

Liquid