NDUFS2 Antilichaam, KO gevalideerd

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) . Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

4720

O75306

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of human NDUFS2 (NP_004541.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 49kDa

IgG

NDUFS2

HeLa

293T

Mouse brain

Mouse kidney

Mouse spleen

NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

Homo sapiens

NDUFS2, NADH-ubiqui oxidoreductase NDUFS2 subunit, NADH dehydrogenase (ubiqui) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase), complex 1, mitochondrial respiratory chain, 49-KD subunit, CI-49

WB, IHC

Liquid