NECAB3 Antilichaam

The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

63941

Q96P71

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-362 of human NECAB3 (NP_112508.3) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 50kDa

IgG

WB: 1:200 - 1:2000

NECAB3

Mouse liver

Rat liver

N-terminal EF-hand calcium binding protein 3

Homo sapiens

APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5, N-terminal EF-hand calcium-binding protein 3, EF-hand calcium binding protein 3, Nek2-interacting protein 1, X11L-binding protein 51, amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein, amyloid beta A4 protein-binding family A member 2-binding protein, neuronal calcium-binding protein 3, neuronal calcium-binding protein NECAB3, synaptotagmin interacting protein 2, synaptotagmin interacting protein STIP3

WB

Liquid