Necrostatine-34
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Necrostatin-34 is a selective inhibitor of RIP1 kinase. IC50s = 667 nM and 134 nM for TNFα in FAD-deficient Jurkat cells and L929 cells respectively. It binds to a site distinct from that of 7-Cl-O-Nec1 (Focus Cat# 10-4544) locking the enzyme in an inactive conformation. Necrostatin-34 acts synergistically with 7-Cl-O-Nec1 to inhibit necroptosis.
Unconjugated
Off-white solid
-20°C
Beschrijving
Necrostatine-34 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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